Systemic absorption of ketoconazole from vaginal pessaries.
نویسندگان
چکیده
منابع مشابه
The characteristics and satisfaction of the patients using vaginal pessaries.
OBJECTIVE To study the characteristics of pelvic organ prolapse (POP) patients that used a pessary. DESIGN Prospective, descriptive study. SETTING Urogynecology Clinic, Ramathibodi Hospital, Faculty of Medicine, Mahidol University. MATERIAL AND METHOD The authors conducted a prospective, observational study. The average age, parity, average body mass index, menopausal age, pessary type, a...
متن کاملSelf-management of vaginal pessaries for pelvic organ prolapse
Two thirds of women opt to use a vaginal pessary initially to manage the symptoms of pelvic organ prolapse. In the UK most women attend a health care professional at least every six months to change the pessary. This represents a significant burden both economically to the health care system and personally for the woman. Annually there are more than 300 appointments for pessary changes at our h...
متن کاملVaginal support pessaries: indications for use and fitting strategies.
Flexible silicone vaginal support pessaries offer a low-risk, effective option for treatment of symptoms of pelvic organ prolapse. This first article in a three-part series summarizes clinical recommendations and current evidence related to pessary indications, choice, and fitting.
متن کاملFormulation and Evaluation of Mucoadhesive Vaginal Films of Ketoconazole
Address for correspondence Mr. Arshad Bashir Khan, Associate Professor, Department of Pharmaceutics, Krupanidhi College of Pharmacy, #12/1, Chikkabellandur, Carmelaram Post, Bangalore560035, India. Phone No: +91 9740379897 E-mail: [email protected] ABSTRACT Purpose: The aim of the present study was to formulate and evaluate mucoadhesive films containing Ketoconazole (KT) for the treatment of vag...
متن کاملTX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol
OBJECTIVE To evaluate the pharmacokinetics of TX-004HR vaginal estradiol softgel capsules when used for treating moderate-to-severe dyspareunia in postmenopausal women with vulvar and vaginal atrophy. METHODS A substudy of the REJOICE trial (multicenter, double-blind, placebo-controlled, phase 3) evaluated the pharmacokinetics of 4, 10, and 25-μg TX-004HR doses once/d for 2 weeks, followed by...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1984
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1984.tb02334.x